During its recent terms, the Supreme Court has taken and decided more intellectual property cases than it did in the previous decade. Many of these decisions—including eBay, MedImmune, KSR and others—were expected to have far-reaching impacts on district courts, the Federal Circuit and IP practitioners. They have. In this installment of our Celesq®-West IP Master Series for the Intellectual Property practitioner, Anthony Lo Cicero discusses the Supreme Court's effect on recent lower court decisions, PTO practices and the way IP law is practiced.